Mudanya University Institutional Academic Archive System
Mudanya University's Dspace system is a platform that digitally stores and opens academic studies. Academic content such as articles, presentations, theses, books, and reports are included here. Dspace@Mudanya provides easy access, making it a valuable resource for researchers and students. It serves as a digital archive for Mudanya University's academic outputs, facilitates access to scientific information and supports its sharing. For more information and assistance, please contact us.
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Atrial Fibrillation Among ICU Patients with Type 2 Respiratory Failure: Who Is at Risk and What Are the Outcomes?
(MDPI, 2025-06) Mentes, Oral; Celik, Deniz; Yıldız, Murat; Özdemir, Tarkan; Güllü, Yusuf Taha; 156045
Background: Atrial fibrillation (AF) frequently occurs in individuals with hypercapnic type 2 respiratory failure and has the potential to adversely affect patient outcomes. This study sought to investigate the clinical features and prognostic significance of atrial fibrillation in patients admitted to the intensive care unit with hypercapnic type 2 respiratory failure. Methods: This retrospective, single-center study included 200 adult patients diagnosed with hypercapnic type 2 respiratory failure between May 2022 and May 2023. Patients were grouped according to whether atrial fibrillation was present or not. Demographic, laboratory, and echocardiographic findings, comorbidities, and outcomes were compared. Kaplan–Meier survival analysis and Cox regression were used to identify mortality predictors. Results: AF was present in 50.5% of patients. Those with AF were older, had higher Charlson Comorbidity Index scores, and a greater prevalence of heart failure (p < 0.001). No significant differences were found in arterial blood gas values. AF patients had higher urea, creatinine, and BNP levels, and lower hemoglobin, lymphocyte, eosinophil, and monocyte counts (p < 0.05). Echocardiography showed more severe tricuspid and mitral regurgitation, lower ejection fractions, and higher systolic pulmonary pressures in the AF group. About 20% of AF patients were not receiving anticoagulants at ICU admission. AF was associated with shorter survival (49.6 ± 4.07 vs. 61.4 ± 3.8 days, p = 0.031) and 1.6-fold higher mortality risk (HR: 1.60, 95% CI: 1.04–2.47). Advanced age and low hemoglobin were independent predictors of mortality. Conclusions: AF is frequent among patients with type 2 respiratory failure and is linked to increased mortality. Despite known complications, treatment remains underutilized. AF should be actively screened during ICU admissions for respiratory failure.
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Patients' Expectations and Satisfaction Regarding to the Protection of Their Individual Dignity After Surgery: A Cross-Sectional Study
(Wiley, 2025-05) Güneş, Ayşegül; Eren, Esra; Tekin, Yasemin Eda; 292320
This study aimed to determine patients' expectations and satisfaction regarding protecting their dignity after surgery. This descriptive, cross-sectional study was conducted with 385 patients between December 2024 and February 2025. Research data was collected using the "Inpatient Dignity Scale" and socio-demographic information form. It was determined that the patient's dignity scale expectation and satisfaction total scores were 72.85 +/- 4.509 and 85.03 +/- 8.011. Accordingly, the expectation scores of the young, those with higher education levels, those whose income is lower than their expenses, those who have had surgery before, those who can perform activities of daily living those who can do it with assistance, those who can connect the head and neck are significantly stronger (p < 0.05). The satisfaction scores of the married, those with the highest and lowest education levels, those whose income is lower than their expenses, those who have had a longer hospital stay after surgery, and those who have had head and neck surgery are higher (p < 0.05). New studies should be conducted in surgical units where nursing activities to protect patient dignity are planned, and their results are evaluated.
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Effect of Limosilactobacillus reuteri DSM17938 to prevent antibiotic-associated diarrhea in children: prospective, multi-center, randomized, placebo-controlled clinical trial (PEARL Study)
(Springer, 2025-06) Dinleyici, Ener Çağrı; Özen, Metehan; Güven, Şirin; Dalgıç, Nazan; Karbuz, Adem; Sütçü, Murat; Yazar, Ahmet Sami; 243394
Antibiotic-associated diarrhea (AAD) is one of the side effects that occur during and after antibiotic use. Some probiotics have strain-specific beneficial effects on AAD development when used in combination with antibiotics. The aim of this study was to evaluate the effect of Limosilactobacillus reuteri DSM 17938 on the prevention of AAD in children. This is a prospective, multicenter, randomized, double-blind, placebo-controlled clinical trial in T & uuml;rkiye between 2017-2019, among outpatient children with acute otitis media (AOM) or acute rhinosinusitis (ARS). Group 1 (n = 330) received amoxicillin-clavulanate and L. reuteri DSM 17938 (2 x 10(8) CFU) and Group 2 (n = 324) received amoxicillin-clavulanate and a placebo during the antibiotic treatment or continued for 21 days after antibiotic cessation. The primary end point of this study was the percentage of children with AAD in the first 14, 21, and 56 days of follow-up. Secondary endpoints are the percentage of children with AAD regarding the AOM vs ARS, amoxicillin-clavulanate dose, age groups, and the comparison between 14- and 21-days use of L. reuteri. The percentage of children with AAD was significantly lower in the L. reuteri group compared to the placebo group at 14 days (7.9% vs. 16.7%; RR: 0.47, 95%CI 0.30-0.7; p < 0.001); at 21 days (8.8% vs. 17.9%; RR: 0.49, 95%CI 0.32-0.74;p < 0.001); and at 56 days (9.1% vs. 19.6%; RR: 0.46, 95%CI 0.30-0.69;p < 0.001). The incidence of AAD was also significantly lower in the L. reuteri group at 14, 21 and 56 days among children aged between 6-24 months (p < 0.01, p < 0.01, p < 0.001) or children with AOM (p = 0.0001,p < 0.0001,p < 0.0001). When AAD was observed, the mean duration of diarrhea was longer in the placebo group(p < 0.05). Conclusions: This first study with L. reuteri DSM 17938 in a large pediatric outpatient setting showed significant reduction of AAD during the first 14 days of antibiotic use and the 8-week follow-up period. Trial Registration: NCT02765217 (First Submitted 02.05.2016) (https://clinicaltrials.gov/study/NCT02765217?term=NCT02765217&rank=1).
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Integrating technology into English language teaching at Indonesian high schools: Teachers’ reflections
(Universitas Syiah Kuala, 2025-05) Anwar, Choiril; Hartono, Hartono; Yavuz, Fatih; 131069
English Language Teaching (ELT) is something that has changed dramatically in recent times due to technology. Even though it could potentially reshape ELT, appropriate implementation remains a challenge for most teachers who are often uncertain as to how to use technology to improve learning. This article looks into the experiences and reflections of Indonesian high school English teachers integrating technology into their ELT pedagogical practices, from making lesson plans, having classroom activities, to setting up the assessment. Quantitative and qualitative data were collected and analyzed through a mixed-methods approach. It involved an online survey distributed to 20 diverse Indonesian high school English teachers as well as semi-structured interviews conducted with 10 teachers. The results indicated that there is an increasing use of technology for ELT purposes, particularly to facilitate language reception, language production, and interaction. The results also found some challenges and limitations, including technical issues, training and support, and access equity. These insights can help guide the future development of Indonesian high school ELT practices, inform investment in technology infrastructure, and support targeted professional development initiatives focused on technology integration. The findings are discussed in the context of existing research on ELT and technology integration, with particular emphasis on their significance for high school English teachers in Indonesia. The results provide implications for ELT policymakers, practitioners, and researchers in Indonesia and evidence the importance of context-sensitive solutions to provide meaningful integration of technology in the variability of Indonesian high school settings.
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Development of Diallyl Phthalate-Filled Ceramic Shell Self-Healing Capsules for High-Temperature Polymer Composites
(MDPI, 2025-06) Yazıcı, Murat; Karaman, Aycan; Şahin, Eslem; Duran, Gönenç; 414011; 370010
In this study, a production method for ceramic shell macrocapsules and a high-temperature-resistant, polymer agent-based self-healing system was developed. Two types of macrocapsules were created by filling hollow ceramic capsules with high-temperature-resistant diallyl phthalate (DAP) resin, known for its thermal stability, and a peroxide-based curing agent. These capsules were incorporated into epoxy and DAP matrix materials to develop polymer composite materials with self-healing properties The macrocapsules were produced by coating polystyrene (PS) sacrificial foam beads with raw ceramic slurry, followed by sintering to convert the liquid phase into a solid ceramic shell. Moreover, FTIR, TGA/DTA, and DSC analyses were performed. According to the thermal analysis results, DAP resin can effectively function as a healing agent up to approximately 340 °C. In addition, quasi-static compression tests were applied to composite specimens. After the first cycle, up to 69% healing efficiency was obtained in the epoxy matrix composite and 63.5% in the DAP matrix composite. Upon reloading, the second-cycle performance measurements showed healing efficiencies of 56% for the DAP matrix composite and 58% for the epoxy matrix composite.
