Mudanya University Institutional Academic Archive System
Mudanya University's Dspace system is a platform that digitally stores and opens academic studies. Academic content such as articles, presentations, theses, books, and reports are included here. Dspace@Mudanya provides easy access, making it a valuable resource for researchers and students. It serves as a digital archive for Mudanya University's academic outputs, facilitates access to scientific information and supports its sharing. For more information and assistance, please contact us.
Communities in DSpace
Select a community to browse its collections.
Now showing 1 - 3 of 3
Recent Submissions
Item
The Relationship between Resistant Hypertension and Advanced Glycation End-Product Levels Measured Using the Skin Autofluorescence Method: A Case–Control Study
(MDPI, 2023-10) Peker, Tezcan; Boyraz, Bedrettin; 313898
Resistant hypertension is hypertension that cannot be controlled despite the use of three antihypertensive drugs, one of which is a diuretic. Resistant hypertension often coexists with advanced age, obesity, smoking, and diabetes. Advanced glycation end products (AGEs) are substances that are generated as a result of the glycation of proteins, lipids, and nucleic acids due to conditions such as hyperlipidemia, oxidative stress, and hyperglycemia. There are studies showing the relationships between AGE levels and aortic stiffness, hypertension, and microvascular and macrovascular complications in diabetes. In our study, we examined the relationship between resistant hypertension and AGE levels. Our study was planned as a case–control study, and 88 patients with resistant hypertension were included in the focus group, while 88 patients with controlled hypertension were included in the control group. The AGE levels of the patients were measured using the skin autofluorescence method. AGE levels were found to be significantly higher in patients with resistant hypertension than those recorded in the control group. A significant increase in AGE levels was also observed in patients with resistant hypertension and without diabetes compared with the control group. The levels of AGEs, which can be measured cheaply, noninvasively, and quickly with the skin autofluorescence method, may provide benefits in identifying these patients with resistant hypertension.
Item
Post-2023 Türkiye earthquake risk assessment of cascade dams in upper Euphrates basin
(Elsevier, 2024-12) Tosun, Hasan; Hariri-Ardebili, Mohammad Amin
The southeastern region of Türkiye faced two significant earthquakes on February 6, 2023, causing widespread destruction and substantial damage to various infrastructures. Over forty large dams in the region were affected, leading to potential new earthquake-prone areas due to energy accumulation in neighboring regions. This study focuses on the seismic risk of eight cascade dams on the Peri River, a tributary of the Euphrates main river, following these earthquakes. The dams, including Kalecik, Kigi, Konaktepe, Ozluce, Pempelik, Seyrantepe, Tatar, and Uzuncayir, with heights ranging from 31 m to 146 m, are situated in a region influenced by the North Anatolian Fault Zone. The research advocates for a comprehensive re-analysis of certain large dams, considering the updated seismic specifications and seismological maps of Türkiye. The study explores the hazard and overall risk assessment of these dams, emphasizing the cascade system and highlighting the critical seismic vulnerabilities of Kigi and Ozluce dams, with a particular focus on their implications for water security in the region. Our findings underscore the need for tailored safety measures for each dam, focusing on early defect detection. By adopting a proactive stance and implementing our recommendations, the resilience of these dams can be enhanced, contributing to the overall water security of the region.
Item
Multi-inflammatory index as a novel predictor of new-onset atrial fibrillation after off-pump coronary artery bypass grafting
(Polish Cardiac Soc, 2024-05) Yüksel, Ahmet; Velioğlu, Yusuf; Atasoy, Mustafa Selçuk; Müdüroğlu, Ayhan; Deşer, Serkan Burç; Gürbüz, Orçun; Aldemir, Mustafa; Çetintaş, Demir; Kılıç, Ali Önder; Badem, Serdar
Background: To our knowledge, a possible predictive relationship of the multi-inflammatory index (MII) with new-onset atrial fibrillation (AF) after off-pump coronary artery bypass grafting (CABG) has not yet been studied in the literature. Aims: We aimed to investigate whether the MII is a novel group of hematological markers for predicting postoperative new-onset AF in patients undergoing off-pump CABG. Methods: A total of 427 patients undergoing isolated off-pump CABG between October 2021 and December 2023 were enrolled in this retrospective observational cohort study and allocated to two groups: the AF group (n = 108) and the non-AF group (n = 319). The groups were compared in terms of baseline clinical patient characteristics, laboratory parameters, and operative and postoperative data. Results: The median values of age, length of hospital stay, platelet and neutrophil count, C-reactive protein level, systemic immune-inflammation index, MII-1, MII-2, and MII-3 were significantly greater in the AF group compared to the non-AF group in univariate analyses. In multiple explanatory variable logistic regression analysis, MII-1, MII-2, and MII-3 were determined to be significant hematological variables, and thereby these indices were considered the independent predictors of postoperative new-onset AF. Receiver operating characteristic curve analyses showed that to predict postoperative new-onset AF, MII-1 of 22.47 constituted the cut-off value with 62.0% sensitivity and 57.0% specificity, MII-2 of 141.77 constituted the cut-off value with 43.5% sensitivity and 76.8% specificity, and MII-3 of 5669 constituted the cut-off value with 63.8% sensitivity and 58.3% specificity. Conclusion: This study demonstrated for the first time that all MIIs predicted new-onset AF after off-pump CABG.
Item
Effect of stress conditions on concentrated leak erosion resistant of fine-grained soils with different characteristics
(Springer, 2024-08) Topçu, Sadettin; Savaş, Hasan; Tosun, Hasan
Internal erosion is one of the most important factors that cause earth structures that retain water, such as embankment dams, to collapse. Concentrated leak erosion, one of the forms of internal erosion, occurs in cracked fine-grained soils and pressurized flow conditions. To evaluate the concentrated leak erosion risk of cracks/voids, it is necessary to ascertain the erosion resistance of these materials. The erosion rate and critical shear stresses determine internal erosion resistance in concentrated leak erosion. This study determined soil’s concentrated leak erosion resistance using test equipment that allowed the flow to pass through a hole with stress-free (no loading), anisotropic-compression stress, anisotropic-expansion stress, and isotropic stress conditions. The stresses that developed in the samples’ hole wall where erosion occurred were determined with numerical modeling as pre-experimental stress conditions. The experiments were performed under a single hydraulic head on four selected cohesive soils with different erosion sensitivity. Time-dependent flow rates obtained from the test system can be used to determine hydraulic parameters, such as energy grade lines, with the help of basic theorems of pipe hydraulics in theoretical hydraulic models. Moreover, the erosion rates were quantitatively determined using the continuity equation, while critical shear stresses were qualitatively compared for concentrated leak erosion developed by the dispersion mechanism. As a result of the experiments, stress conditions influence the concentrated leak erosion resistance in the soil samples with dispersive erosion. Moreover, the shear strength in the Mohr–Coulomb hypothesis can explain the erosion resistance in these soils under stress conditions depending on the sand/clay ratio.
Item
Relationship between maritime transport and economic growth: highest maritime transport european countries
(Ordu University, 2025-01) Canbay, Şerif; Kırca, Mustafa; 278780
Maritime transport is one of the most widely used transport channels used by countries in foreign trade. The development of maritime transport affects the economic growth levels of countries. In addition, the increase in the level of economic growth of countries increases their share in international foreign trade and this situation increases the importance given by countries to maritime transport day by day. The identification of the effects of maritime transport in countries will provide important information on what countries should do against the shocks they will face in the future. In this context, the study aims to determine whether there is any causality relationship between maritime transport and economic growth variables in Belgium, France, Germany, Italy, Netherlands, Spain, Türkiye, and the United Kingdom, which have the highest maritime transport among European countries. The bootstrap panel causality test was employed to examine the causality relationships between the variables over the time frame of 2008:Q1-2020:Q2. According to the findings, there is a causality relationship from economic growth to maritime transport in all countries except Italy and the Netherlands. There is a causality relationship from maritime transport to economic growth in Türkiye and the United Kingdom. As a result, the relationship between maritime transport and economic growth varies from country to country. This situation reveals the necessity of developing national policies for maritime transport by considering the economic structures of the countries. These findings suggest that countries need more efficient and sustainable maritime transport policies.
