Multi-inflammatory index as a novel predictor of new-onset atrial fibrillation after off-pump coronary artery bypass grafting
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Date
2024-05
Authors
Yüksel, Ahmet
Velioğlu, Yusuf
Atasoy, Mustafa Selçuk
Müdüroğlu, Ayhan
Deşer, Serkan Burç
Gürbüz, Orçun
Aldemir, Mustafa
Çetintaş, Demir
Kılıç, Ali Önder
Badem, Serdar
Journal Title
Journal ISSN
Volume Title
Publisher
Polish Cardiac Soc
Abstract
Background: To our knowledge, a possible predictive relationship of the multi-inflammatory index (MII) with new-onset atrial fibrillation (AF) after off-pump coronary artery bypass grafting (CABG) has not yet been studied in the literature. Aims: We aimed to investigate whether the MII is a novel group of hematological markers for predicting postoperative new-onset AF in patients undergoing off-pump CABG. Methods: A total of 427 patients undergoing isolated off-pump CABG between October 2021 and December 2023 were enrolled in this retrospective observational cohort study and allocated to two groups: the AF group (n = 108) and the non-AF group (n = 319). The groups were compared in terms of baseline clinical patient characteristics, laboratory parameters, and operative and postoperative data. Results: The median values of age, length of hospital stay, platelet and neutrophil count, C-reactive protein level, systemic immune-inflammation index, MII-1, MII-2, and MII-3 were significantly greater in the AF group compared to the non-AF group in univariate analyses. In multiple explanatory variable logistic regression analysis, MII-1, MII-2, and MII-3 were determined to be significant hematological variables, and thereby these indices were considered the independent predictors of postoperative new-onset AF. Receiver operating characteristic curve analyses showed that to predict postoperative new-onset AF, MII-1 of 22.47 constituted the cut-off value with 62.0% sensitivity and 57.0% specificity, MII-2 of 141.77 constituted the cut-off value with 43.5% sensitivity and 76.8% specificity, and MII-3 of 5669 constituted the cut-off value with 63.8% sensitivity and 58.3% specificity. Conclusion: This study demonstrated for the first time that all MIIs predicted new-onset AF after off-pump CABG.
Description
Science Citation Index Expanded (SCI-EXPANDED)
Keywords
atrial fibrillation , coronary artery bypass grafting , multi-inflammatory index , off-pump , predictor
Citation
Yüksel, A., Velioğlu, Y., Atasoy, M. S., Müdüroğlu, A., Gürbüz, O., Aldemir, M., Deşer, S. B., Çetintaş, D., Kılıç, A. O. & Badem, S. (2024). Multi-inflammatory index as a novel predictor of new-onset atrial fibrillation after off-pump coronary artery bypass grafting. Polish Heart Journal (Kardiologia Polska). 82(7-8), 733-740. https://doi.org/10.33963/v.phj.100847
